Kaempferol and Kaempferol Rhamnosides with Depigmenting and Anti-Inflammatory Properties

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Kaempferol and kaempferol rhamnosides with depigmenting and anti-inflammatory properties.

The objective of this study was to examine the biological activity of kaempferol and its rhamnosides. We isolated kaempferol (1), a-rhamnoisorobin (2), afzelin (3), and kaempferitrin (4) as pure compounds by far-infrared (FIR) irradiation of kenaf (Hibiscus cannabinus L.) leaves. The depigmenting and anti-inflammatory activity of the compounds was evaluated by analyzing their structure-activity...

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In vitro anti-HIV-1 activities of kaempferol and kaempferol-7-O-glucoside isolated from Securigera securidaca

Previously, we reported that the kaempferol and kaempferol-7-O-glucoside isolated from Securigera securidaca showed potent anti-HSV activity. In the present study the anti-HIV-1 activities of kaempferol and kaempferol-7-O-glucoside are investigated at different concentrations (100, 50, 25 and 10 μg/ml) using HIV-1 p24 Antigen kit. Real-time Polymerase chain reaction (RT-PCR) assay was also used...

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Selective methylation of kaempferol via benzylation and deacetylation of kaempferol acetates

A strategy for selective mono-, di- and tri-O-methylation of kaempferol, predominantly on the basis of selective benzylation and controllable deacetylation of kaempferol acetates, was developed. From the selective deacetylation and benzylation of kaempferol tetraacetate (1), 3,4',5,-tri-O-acetylkaempferol (2) and 7-O-benzyl-3,4'5,-tri-O-acetylkaempferol (8) were obtained, respectively. By contr...

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Kaempferol from Saffron Petals

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Kaempferol Attenuates the Development of Diabetic Neuropathic Pain in Mice: Possible Anti-Inflammatory and Anti-Oxidant Mechanisms

Abbreviations: Diabetic neuropathic pain (DNP), diabetic neuropathy (DN), diabetic mice (DM), oxidative stress (OS), inflammatory cytokines (IC), interleukin-1β (IL-1β), tumor necrosis factor-α (TNF-α), proinflammatory cytokines (pro-IC), neuropathic pain (NP), nuclear factor-κB (NF-κB), Reactive oxygen species (ROS), nitric oxide (NO), N-methyl-Daspartate (NMDA), mitogen-activated protein kina...

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ژورنال

عنوان ژورنال: Molecules

سال: 2011

ISSN: 1420-3049

DOI: 10.3390/molecules16043338